Every time someone says Hugh Laurie
would make a good Vimes all I can see is HL playing Bertie Wooster or dad in Stuart Little
I know he's a whole lot tougher and hyper-cynical in House but - No!
It's just a push too far I'm afraid.
as Vetinari? I can sort of see that in the attitude department although he's really too flippant, but he's far too cute physically and in a way he's like Pierce Brosnan was playing Bond - you just can't imagine him being really ruthless despite the evidence of your own eyes. Vetinari's not got any playfulness about him at all and JD can't help but do that whoever he's playing.
Now Stephen Fry
(HL's sometime comedy partner) would be brilliant as being Vetinari on the cerebral side of things as he can do cruel snidey, superior intellect and coldly calculating to the nth degree
Pity he's a bit too pampered looking (plump) although he does look a bit like a prize fighter (he's got a glorious broken-looking nose), is very tall and has a decidedly Patricianly manner about him. But he's such a big old softie I don't think he could quite crack it - Charles Dance
is pretty well cast in that role I'd say.