The RAI pill is really no biggie. You just can't be within six feet of Pregnant women, babies, or Pooh for two weeks and you have to flush the Loo two times because your kidneys process it out of your body.
I had a goiter the size of my fist on my neck, it was wonderful when it was gone. Diet and excersize are really important afterwords because, well, you CAN balloon up in the years after if you don't learn how to eat properly and it is a Real Drag to work it off AFTER you gain it. I have complete faith that a healthy diet and a good walk three times a week will do wonders for prevention of ... dare I say it?... *Gasp* cellulite!!!!